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Cheap flights from St. Louis (STL) to Panama from $229

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — PTY
May 21 — May 281
From?
To?
Tue 5/21
Tue 5/28
1 adult, Economy
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What is the cheapest month to fly from St. Louis to Panama?

The best pricing can be found in the month of October. Prices to Panama from St. Louis average $544. You can even find prices in October for less than $544, as users have found deals to Panama from as low as $349. The month of December appears to be one of the more expensive times to travel to Panama from St. Louis. Flying in the targeted month can save you up to 82%.

When is the cheapest time to fly from St. Louis to Panama (STL - PA)?

When flying from St. Louis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Cheap Delta flights from St. Louis to Panama

Explore cheap flight options specifically provided by Delta for the route between St. Louis and Panama. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,637,452 searches. Data last updated May 16, 2024.
Check out some of the cheapest Delta flights we've come across from St. Louis to Panama. Make sure to double check the flight details before booking.
Wed 9/256:00 amSTL - PTY
1 stop6h 55mDelta
Wed 10/92:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 5/16$450
Sat 9/76:00 amSTL - PTY
1 stop6h 55mDelta
Wed 9/112:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 5/15$470

Cheap American Airlines flights from St. Louis to Panama

Explore cheap flight options specifically provided by American Airlines for the route between St. Louis and Panama. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,637,452 searches. Data last updated May 16, 2024.
Some of the lowest-priced American Airlines flights we've found at this time heading from St. Louis to Panama. If these deals don't fit your criteria, make sure to check back soon as new deals are always added.
Wed 9/252:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Wed 10/91:55 pmPTY - STL
2 stops20h 20mAmerican Airlines
Deal found 5/14$453
Thu 8/16:09 pmSTL - PTY
2 stops20h 11mAmerican Airlines
Wed 8/283:14 pmPTY - STL
2 stops17h 05mAmerican Airlines
Deal found 5/15$493
Thu 8/16:09 pmSTL - PTY
2 stops20h 11mAmerican Airlines
Wed 8/283:14 pmPTY - STL
1 stop8h 02mAmerican Airlines
Deal found 5/15$494
Sat 9/76:58 pmSTL - PTY
2 stops17h 35mAmerican Airlines
Wed 9/111:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 5/14$561
Wed 6/125:38 pmSTL - PTY
2 stops18h 51mAmerican Airlines
Wed 6/191:19 pmPTY - STL
2 stops21h 06mAmerican Airlines
Deal found 5/14$623

Cheap St. Louis to Panama flights in May & June 2024

Find cheap flight options from St. Louis to Panama specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,637,452 searches. Prices were last updated on May 16, 2024.
Scroll through some of the best deals on flights from St. Louis to Panama in 2024. More deals are always being added, so be sure to check back regularly.
Wed 6/126:15 amSTL - PTY
1 stop9h 51mUnited Airlines
Wed 6/197:55 amPTY - STL
1 stop14h 20mUnited Airlines
Deal found 5/14$490
Wed 6/126:15 amSTL - PTY
1 stop8h 04mUnited Airlines
Wed 6/1910:55 pmPTY - STL
2 stops15h 19mUnited Airlines
Deal found 5/14$534
Wed 6/125:38 pmSTL - PTY
2 stops18h 51mAmerican Airlines
Wed 6/191:19 pmPTY - STL
2 stops21h 06mAmerican Airlines
Deal found 5/14$623

St. Louis to Panama 2024 flight deals

Discover exclusive flight deals for travel between St. Louis and Panama in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,637,452 searches. Data last updated May 16, 2024.
Scroll through some of the best deals on flights from St. Louis to Panama in 2024. More deals are always being added, so be sure to check back regularly.
Wed 9/256:00 amSTL - PTY
1 stop6h 55mDelta
Wed 10/92:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 5/16$450
Wed 9/252:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Wed 10/91:55 pmPTY - STL
2 stops20h 20mAmerican Airlines
Deal found 5/14$453
Sat 9/76:00 amSTL - PTY
1 stop6h 55mDelta
Wed 9/112:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 5/15$470
Sat 9/76:34 amSTL - PTY
2 stops12h 03mUnited Airlines
Wed 9/113:40 pmPTY - STL
1 stop18h 11mUnited Airlines
Deal found 5/14$474
Wed 6/126:15 amSTL - PTY
1 stop9h 51mUnited Airlines
Wed 6/197:55 amPTY - STL
1 stop14h 20mUnited Airlines
Deal found 5/14$490
Thu 8/16:09 pmSTL - PTY
2 stops20h 11mAmerican Airlines
Wed 8/283:14 pmPTY - STL
2 stops17h 05mAmerican Airlines
Deal found 5/15$493
Thu 8/16:09 pmSTL - PTY
2 stops20h 11mAmerican Airlines
Wed 8/283:14 pmPTY - STL
1 stop8h 02mAmerican Airlines
Deal found 5/15$494
Wed 6/126:15 amSTL - PTY
1 stop8h 04mUnited Airlines
Wed 6/1910:55 pmPTY - STL
2 stops15h 19mUnited Airlines
Deal found 5/14$534
Sat 9/76:58 pmSTL - PTY
2 stops17h 35mAmerican Airlines
Wed 9/111:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 5/14$561

One-way flights to Panama from St. Louis

Search for one-way flight options from St. Louis to Panama. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,637,452 searches. Data last updated May 16, 2024.
Users traveling one-way from St. Louis to Panama can select one of these great deals. Users can also find round-trip St. Louis to Panama flights by using the search form above.
Fri 7/56:00 amSTL - PTY
1 stop13h 56mDelta
Deal found 5/16$229
Fri 7/53:18 pmSTL - PTY
2 stops21h 12mAmerican Airlines
Deal found 5/15$232
Fri 7/53:18 pmSTL - PTY
2 stops21h 12mAmerican Airlines
Deal found 5/16$233
Thu 7/410:15 amSTL - PTY
1 stop26h 37mDelta
Deal found 5/15$234
Thu 7/44:02 pmSTL - PTY
1 stop20h 50mDelta
Deal found 5/16$235
Thu 7/46:22 pmSTL - PTY
2 stops44h 23mMultiple Airlines
Deal found 5/15$266
Thu 7/46:22 pmSTL - PTY
2 stops44h 23mMultiple Airlines
Deal found 5/16$267
Thu 7/46:22 pmSTL - PTY
3 stops26h 23mMultiple Airlines
Deal found 5/15$305
Thu 7/46:22 pmSTL - PTY
3 stops26h 23mMultiple Airlines
Deal found 5/16$306

Find flights from St. Louis to Panama within your budget

Customize your flight search to find flights from St. Louis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,637,452 searches. Data last updated May 16, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$450 - $561

Route

Depart

Return

Price

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/25

1 stop6h 55m

Panama City Tocumen Intl

Wed 10/9

1 stop9h 15m

$450

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/25

2 stops21h 55m

Panama City Tocumen Intl

Wed 10/9

2 stops20h 20m

$453

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 9/7

1 stop6h 55m

Panama City Tocumen Intl

Wed 9/11

1 stop9h 15m

$470

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 9/7

2 stops12h 03m

Panama City Tocumen Intl

Wed 9/11

1 stop18h 11m

$474

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 6/12

1 stop9h 51m

Panama City Tocumen Intl

Wed 6/19

1 stop14h 20m

$490

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Thu 8/1

2 stops20h 11m

Panama City Tocumen Intl

Wed 8/28

2 stops17h 05m

$493

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Thu 8/1

2 stops20h 11m

Panama City Tocumen Intl

Wed 8/28

1 stop8h 02m

$494

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 6/12

1 stop8h 04m

Panama City Tocumen Intl

Wed 6/19

2 stops15h 19m

$534

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 9/7

2 stops17h 35m

Panama City Tocumen Intl

Wed 9/11

2 stops20h 09m

$561

Flights are sorted by cheapest first

Deals found on 5/16

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 16, 2024.
Read through reviews of airlines operating flights from St. Louis to Panama, such as Delta, American Airlines and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
10,673 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

8.0

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Delta
8.0
Very good
10,673 reviews
Delta
8.0
Very good
10,673 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

8.0

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

United Airlines
7.4
Good
10,924 reviews
Delta
8.0
Very good
10,673 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

8.0

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

American Airlines
7.3
Good
14,514 reviews
Delta
8.0
Very good
10,673 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

8.0

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Panama?

    For a flight from St. Louis to Panama, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • Can I find flights from St. Louis to Panama for under $500 on Cheapflights?

    Yes, there are multiple flights from St. Louis to Panama for under $500. The cheapest flight booked recently is on Delta for just $450, but on average you can expect to pay $504.

  • What are the most popular airlines that fly from St. Louis to Panama?

    When booking a flight from St. Louis to Panama, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

  • What does STL to PTY mean?

    Lambert-St Louis Airport is STL and Panama City Tocumen Intl Airport is PTY. These codes are created by the International Air Transport Association (IATA) and airlines use them to identify the departing and arrival airports in the flight routes they service. Panama City Marcos A. Gelabert Intl Airport (PAC), David Enrique Malek Airport (DAV), Panama City Panamá Pacifico Airport (BLB), Bocas Del Toro Airport (BOC), Pedasí Capt. J. Montenegro Airport (PDM) are other airports near this flight route and their unique identifiers/IATA codes.

  • Can I find deals for flights from St. Louis to Panama that include extra baggage allowance?

    The amount of baggage you can bring on your St. Louis to Panama flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from St. Louis to Panama with specific airlines?

    Yes, Cheapflights allows you to browse and filter St. Louis to Panama flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from St. Louis to Panama that include hotel bookings?

    Yes. In addition to deals on St. Louis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama.

  • Can I find deals for business class flights from St. Louis to Panama?

    Yes. Cheapflights offers flight deals from St. Louis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from St. Louis to Panama that allow pets onboard?

    Many airlines flying from St. Louis to Panama offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from St. Louis to Panama?

    Yes, you can often find last-minute deals on St. Louis to Panama flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the St. Louis to Panama flight deals updated?

    The St. Louis to Panama flight deals you see on this page were last updated on 5/16.

See more FAQs

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Alternative routes for St. Louis to Panama
See prices for flight routes from nearby airports that may be better suited for you.

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Top 3 airlines flying from St. Louis to Panama

Discover the top 3 airlines that operate flights from St. Louis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,637,452 searches. Data last updated May 16, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$504FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
United AirlinesCheapest$349Average$419FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
American AirlinesCheapest$356Average$542FlexibilityNo cancel feeOn-time71%
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Search flights from St. Louis to Panama by cabin class

Find flights from St. Louis to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from St. Louis to Panama?

Cheapflights helps you search for flights from St. Louis to Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from St. Louis to Panama?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama from St. Louis.

Can Cheapflights find flights from St. Louis to Panama with no change fees?

Yes, we can. To see specific flights from St. Louis to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from St. Louis to Panama become cheaper?

Not ready to book yet? You can track prices for flights from St. Louis to Panama on Cheapflights with our Price Alert feature and get notified when better prices are available.

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