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Cheap flights from Knoxville to San Francisco (TYS - SFO) from $109

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — SFO
May 10 — May 171
From?
To?
Fri 5/10
Fri 5/17
1 adult, Economy
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The best prices from Knoxville McGhee Tyson to San Francisco are usually found in February or September, booked 47 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Knoxville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2024.

Popular in

March

Cheapest in

February

Round-trip from

$268

One-way from

$179
High demand for flights, 7% potential price rise
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Best time to find cheap flights, 22% potential price drop
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From Knoxville McGhee Tyson to San Francisco
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One-way flight from Knoxville McGhee Tyson to San Francisco
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What is the cheapest day to fly round-trip from Knoxville to San Francisco?

Sunday flights are generally found to be more expensive for flights from Knoxville to San Francisco. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to San Francisco.

How far in advance should I book a flight from Knoxville to San Francisco?

To save on the cost of your flight from Knoxville to San Francisco, book at least 48 days before your planned departure. Booking around this time can save you about 71% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $416 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $705.

What is the cheapest month to fly from Knoxville to San Francisco?

February can be a great time to fly to San Francisco from Knoxville with a flight ticket averaging about $510. Cheapflights users have found deals in the month of February for as cheap as $260. The most expensive prices can be found in the month of March.

When is the cheapest time to fly from Knoxville to San Francisco (TYS - SFO)?

One of the essential ways to save on airfare from Knoxville to San Francisco is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

Cheap Frontier flights from Knoxville to San Francisco

Explore cheap flight options specifically provided by Frontier for the route between Knoxville and San Francisco. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.
Take a look at some of the lowest-priced Frontier flights heading from Knoxville to San Francisco. Deals update often to give you more flight options matching your criteria
Wed 8/286:17 pmTYS - SFO
1 stop8h 41mFrontier
Tue 9/312:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/4$226
Mon 7/110:41 pmTYS - SFO
1 stop11h 30mFrontier
Fri 7/57:42 pmSFO - TYS
1 stop18h 08mFrontier
Deal found 5/2$244
Fri 5/179:02 pmTYS - SFO
1 stop14h 19mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$246
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$247
Fri 7/125:42 pmTYS - SFO
1 stop9h 16mFrontier
Thu 7/1812:58 amSFO - TYS
1 stop12h 44mFrontier
Deal found 5/4$262
Wed 9/46:17 pmTYS - SFO
1 stop8h 41mFrontier
Sun 9/812:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/3$268
Fri 7/125:42 pmTYS - SFO
1 stop9h 16mFrontier
Fri 7/197:42 pmSFO - TYS
1 stop18h 08mFrontier
Deal found 5/4$270
Sat 9/215:40 pmTYS - SFO
1 stop9h 18mFrontier
Tue 9/2412:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/3$288
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Fri 5/2412:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/4$291

Cheap American Airlines flights from Knoxville to San Francisco

Explore cheap flight options specifically provided by American Airlines for the route between Knoxville and San Francisco. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.
Some of the best deals we've found on American Airlines flights traveling from Knoxville to San Francisco. Ensure the flight price, dates, time, and airline match your criteria before you book.
Wed 8/284:15 pmTYS - SFO
1 stop7h 38mAmerican Airlines
Wed 9/46:00 amSFO - TYS
1 stop8h 29mAmerican Airlines
Deal found 5/4$245
Thu 9/196:25 pmTYS - SFO
1 stop7h 23mAmerican Airlines
Tue 9/246:00 amSFO - TYS
1 stop6h 47mAmerican Airlines
Deal found 5/3$275
Sat 9/216:25 pmTYS - SFO
1 stop7h 23mAmerican Airlines
Tue 9/2412:54 amSFO - TYS
1 stop9h 33mAmerican Airlines
Deal found 5/4$306
Mon 5/275:30 amTYS - SFO
1 stop8h 14mAmerican Airlines
Thu 5/3012:27 pmSFO - TYS
1 stop8h 51mAmerican Airlines
Deal found 5/4$308
Wed 5/296:31 pmTYS - SFO
1 stop8h 50mAmerican Airlines
Mon 6/311:52 pmSFO - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/4$331
Mon 5/275:30 amTYS - SFO
1 stop8h 14mAmerican Airlines
Sat 6/111:52 pmSFO - TYS
1 stop9h 16mAmerican Airlines
Deal found 5/2$336
Fri 6/76:24 pmTYS - SFO
1 stop9h 07mAmerican Airlines
Mon 6/241:06 pmSFO - TYS
1 stop7h 52mAmerican Airlines
Deal found 5/4$361
Thu 6/66:11 pmTYS - SFO
1 stop8h 01mAmerican Airlines
Tue 6/1111:57 pmSFO - TYS
1 stop8h 17mAmerican Airlines
Deal found 5/3$366
Thu 7/256:25 pmTYS - SFO
1 stop8h 56mAmerican Airlines
Tue 7/3011:51 pmSFO - TYS
1 stop8h 22mAmerican Airlines
Deal found 5/3$368

Cheap Knoxville to San Francisco flights in May & June 2024

Find cheap flight options from Knoxville to San Francisco specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,795,183 searches. Prices were last updated on May 5, 2024.
Scroll through some of the best deals on flights from Knoxville to San Francisco in 2024. If these deals don't appeal to you, be sure to come back soon for more options.
Fri 5/179:02 pmTYS - SFO
1 stop14h 19mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$246
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$247
Mon 5/1310:51 amTYS - SFO
1 stop10h 39mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$258
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Fri 5/2412:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/4$291
Sat 5/185:27 pmTYS - SFO
1 stop9h 32mFrontier
Fri 5/2412:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/4$293
Fri 5/314:01 pmTYS - SFO
1 stop10h 58mFrontier
Tue 6/412:59 amSFO - TYS
1 stop14h 48mFrontier
Deal found 5/4$304
Mon 5/275:30 amTYS - SFO
1 stop8h 14mAmerican Airlines
Thu 5/3012:27 pmSFO - TYS
1 stop8h 51mAmerican Airlines
Deal found 5/4$308
Mon 5/1310:51 amTYS - SFO
1 stop10h 39mFrontier
Fri 5/2412:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/4$310
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Sun 5/1912:59 amSFO - TYS
1 stop13h 39mFrontier
Deal found 5/4$320

Knoxville to San Francisco 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and San Francisco in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.
Scroll through some of the best deals on flights from Knoxville to San Francisco in 2024. If these deals don't appeal to you, be sure to come back soon for more options.
Wed 8/286:17 pmTYS - SFO
1 stop8h 41mFrontier
Tue 9/312:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/4$226
Wed 8/284:15 pmTYS - SFO
1 stop7h 38mAmerican Airlines
Wed 9/46:00 amSFO - TYS
1 stop8h 29mAmerican Airlines
Deal found 5/4$245
Fri 5/179:02 pmTYS - SFO
1 stop14h 19mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$246
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$247
Mon 5/1310:51 amTYS - SFO
1 stop10h 39mFrontier
Tue 5/2112:59 amSFO - TYS
1 stop12h 32mFrontier
Deal found 5/4$258
Fri 7/125:42 pmTYS - SFO
1 stop9h 16mFrontier
Thu 7/1812:58 amSFO - TYS
1 stop12h 44mFrontier
Deal found 5/4$262
Fri 7/125:42 pmTYS - SFO
1 stop9h 16mFrontier
Fri 7/197:42 pmSFO - TYS
1 stop18h 08mFrontier
Deal found 5/4$270
Thu 9/196:25 pmTYS - SFO
1 stop7h 23mAmerican Airlines
Tue 9/2411:59 pmSFO - TYS
1 stop7h 20mAmerican Airlines
Deal found 5/4$275
Wed 5/1510:51 amTYS - SFO
1 stop23h 59mFrontier
Fri 5/2412:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/4$291

Knoxville to San Francisco flights leaving soon

Find last-minute flight options from Knoxville to San Francisco for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.
Users seeking a last-minute flight from Knoxville to San Francisco should consider booking one of these fares. Users should examine the flight details to ensure there are no surprises.
Mon 5/1310:51 amTYS - SFO
1 stop10h 39mFrontier
Sun 5/1912:59 amSFO - TYS
1 stop13h 39mFrontier
Deal found 5/4$340
Sat 5/116:31 pmTYS - SFO
1 stop7h 10mAmerican Airlines
Sat 5/2511:34 amSFO - TYS
1 stop9h 44mAmerican Airlines
Deal found 5/3$378
Tue 5/142:30 pmTYS - SFO
1 stop7h 23mAmerican Airlines
Tue 5/219:00 amSFO - TYS
1 stop9h 48mAmerican Airlines
Deal found 5/4$411
Tue 5/146:50 pmTYS - SFO
1 stop8h 22mDelta
Mon 5/2010:45 pmSFO - TYS
1 stop8h 26mDelta
Deal found 5/4$413
Tue 5/146:50 pmTYS - SFO
1 stop8h 22mDelta
Sun 5/1911:51 pmSFO - TYS
1 stop7h 20mDelta
Deal found 5/4$448
Thu 5/912:38 pmTYS - SFO
1 stop10h 11mAmerican Airlines
Thu 5/231:47 pmSFO - TYS
1 stop8h 16mAmerican Airlines
Deal found 5/3$450
Thu 5/911:07 amTYS - SFO
1 stop10h 11mAmerican Airlines
Tue 6/111:43 pmSFO - TYS
1 stop7h 41mAmerican Airlines
Deal found 5/4$451
Sat 5/115:30 amTYS - SFO
1 stop8h 14mAmerican Airlines
Sat 5/2512:59 pmSFO - TYS
2 stops8h 19mAmerican Airlines
Deal found 5/3$453
Mon 5/1310:51 amTYS - SFO
1 stop10h 39mFrontier
Thu 5/2312:59 amSFO - TYS
1 stop15h 40mFrontier
Deal found 5/4$457

One-way flights to San Francisco from Knoxville

Search for one-way flight options from Knoxville to San Francisco. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.
Users traveling one-way from Knoxville to San Francisco can select one of these great deals. Users in need of a round-trip flight from Knoxville to San Francisco instead should update the search form at the top of page.
Wed 9/186:17 pmTYS - SFO
1 stop8h 41mFrontier
Deal found 5/3$109
Mon 6/1710:41 pmTYS - SFO
1 stop11h 30mFrontier
Deal found 5/4$129
Mon 7/156:17 pmTYS - SFO
1 stop8h 41mFrontier
Deal found 5/3$130
Fri 7/125:42 pmTYS - SFO
1 stop9h 16mFrontier
Deal found 5/3$149
Fri 6/710:32 pmTYS - SFO
1 stop28h 27mFrontier
Deal found 5/4$159
Fri 6/2810:32 pmTYS - SFO
1 stop28h 37mFrontier
Deal found 5/3$179
Fri 6/77:25 pmTYS - SFO
3 stops30h 27mMultiple Airlines
Deal found 5/4$243
Mon 6/1711:21 amTYS - SFO
2 stops14h 31mMultiple Airlines
Deal found 5/4$253
Fri 7/1211:49 amTYS - SFO
2 stops26h 52mMultiple Airlines
Deal found 5/3$258

Find flights from Knoxville to San Francisco within your budget

Customize your flight search to find flights from Knoxville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$226 - $461

Route

Depart

Return

Price

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Wed 8/28

1 stop8h 41m

San Francisco

Tue 9/3

1 stop13h 19m

$226

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Mon 7/1

1 stop11h 30m

San Francisco

Fri 7/5

1 stop18h 08m

$244

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Wed 8/28

1 stop7h 38m

San Francisco

Wed 9/4

1 stop8h 29m

$245

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Fri 5/17

1 stop14h 19m

San Francisco

Tue 5/21

1 stop12h 32m

$246

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Wed 5/15

1 stop23h 59m

San Francisco

Tue 5/21

1 stop12h 32m

$247

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 9/19

1 stop7h 23m

San Francisco

Tue 9/24

1 stop6h 47m

$275

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 7/4

1 stop9h 51m

San Francisco

Sat 7/13

1 stop6h 24m

$303

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Sat 6/29

2 stops21h 11m

San Francisco

Thu 7/4

1 stop16h 14m

$392

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Sun 5/26

1 stop8h 11m

San Francisco

Sat 6/1

1 stop7h 40m

$461

Flights are sorted by cheapest first

Deals found on 5/4

When is the best time to book a flight from Knoxville to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Francisco. Price data was last updated on May 3, 2024.
The best time to book flights from Knoxville to San Francisco is 47 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Search Deals

When is the cheapest time to fly from Knoxville to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to San Francisco. Price data was last updated on April 28, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Knoxville to San Francisco flight should consider departing on Monday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Average price of flights to San Francisco by month

Plan your trip from Knoxville to San Francisco by taking into account the cheapest months to travel. The average price of a one-way flight from Knoxville to San Francisco is currently $179 while a round-trip flight costs $293. Price data was last updated on April 28, 2024.

Currently, September is the cheapest month in which you can book a flight from Knoxville to San Francisco (average of $268). Flying from Knoxville to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

January

$274

February

$281

March

$330

April

$306

May

$314

June

$384

July

$367

August

$298

September

$268

October

$268

November

$287

December

$268

Temperature and rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature and rainfall totals by month.

SFO

Temperature

51.8 - 62.6 °F

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 5, 2024.
Read reviews from past customers who have flown Frontier, American Airlines and Delta from Knoxville to San Francisco. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.1
Very good
10,838 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

Delta
8.1
Very good
10,838 reviews
Delta
8.1
Very good
10,838 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

United Airlines
7.4
Good
11,125 reviews
Delta
8.1
Very good
10,838 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

American Airlines
7.3
Good
14,728 reviews
Delta
8.1
Very good
10,838 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

Frontier
6.3
Okay
4,098 reviews
Delta
8.1
Very good
10,838 reviews
Check prices

Food

7.4

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find flights from Knoxville to San Francisco for under $300 on Cheapflights?

    Yes, there are multiple flights from Knoxville to San Francisco for under $300. The cheapest flight booked recently is on Frontier for just $226, but on average you can expect to pay $284.

  • Are there last-minute flights available from Knoxville to San Francisco for under $400?

    There are currently 20+ open flights from Knoxville to San Francisco within the next 7 days for less than $400.

  • What are the cheapest airlines flying from Knoxville to San Francisco round-trip?

    Flying on Frontier is currently your cheapest option to San Francisco, with prices starting at $226. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $245 and $303, respectively. Frontier is priced at 55% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Knoxville to San Francisco one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $109. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Knoxville to San Francisco for a low price.

  • What are the most popular airlines that fly from Knoxville to San Francisco?

    Before booking your flight from Knoxville to San Francisco check out the most popular airlines for this route: American Airlines, Delta or Frontier.

  • What does TYS to SFO mean?

    TYS and SFO are unique codes to identify airports used in the aviation industry. They are defined by IATA (International Air Transport Association) and are commonly called IATA codes. TYS to SFO refers to a flight route from Knoxville McGhee Tyson Airport to San Francisco Airport.

  • Can I find deals for flights from Knoxville to San Francisco that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to San Francisco flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to San Francisco with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to San Francisco flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Francisco.

  • Can I find deals for business class flights from Knoxville to San Francisco?

    Yes. Cheapflights offers flight deals from Knoxville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to San Francisco that allow pets onboard?

    Many airlines flying from Knoxville to San Francisco offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to San Francisco?

    Yes, you can often find last-minute deals on Knoxville to San Francisco flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to San Francisco flight deals updated?

    The Knoxville to San Francisco flight deals you see on this page were last updated on 5/4.

See more FAQs

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Top 4 airlines flying from Knoxville to San Francisco

Discover the top 4 airlines that operate flights from Knoxville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,795,183 searches. Data last updated May 5, 2024.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$183Average$277FlexibilityNo cancel feeOn-time62%
Search Frontier flights
DeltaCheapest$266Average$478FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
American AirlinesCheapest$304Average$520FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
United AirlinesCheapest$367Average$623FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
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