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Cheap flights from St. Louis (STL) to Panama City (PTY) from $450

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — PTY
May 4 — May 111
From?
To?
Sat 5/4
Sat 5/11
1 adult, Economy
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The best prices from Lambert-St Louis to Panama City Tocumen Intl are usually found in October or September, booked 31 days in advance, depart on a Thursday or Wednesday and return on a Thursday

Cheap flight deals from St. Louis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2024.

Popular in

December

Cheapest in

October

Average price

$600

Round-trip from

$474
High demand for flights, 40% potential price rise
Search Deals
Best time to find cheap flights, 40% potential price drop
Search Deals
Average for round-trip flights in April 2024
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From Lambert-St Louis to Panama City Tocumen Intl
Search Deals

What is the cheapest day to fly round-trip from St. Louis to Panama City?

It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from St. Louis to Panama City?

October is one of the best times of the year to fly to Panama City from St. Louis. Prices for October average $637 per person but you can even find prices for as low as $349. The most expensive prices can be found in the month of December. Opting for a October flight can save you 67% on your journey compared to booking in December

When is the cheapest time to fly from St. Louis to Panama City (STL - PTY)?

When flying from St. Louis to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 56% versus a flight in the evening.

Cheap Delta flights from St. Louis to Panama City

Explore cheap flight options specifically provided by Delta for the route between St. Louis and Panama City. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,944,896 searches. Data last updated April 29, 2024.
Check out some of the cheapest Delta flights we've come across from St. Louis to Panama City. Be sure to come back soon if the deals available don't appeal to you at this time.
Wed 9/256:00 amSTL - PTY
1 stop6h 55mDelta
Thu 10/102:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 4/28$450
Sun 9/226:00 amSTL - PTY
1 stop6h 55mDelta
Tue 10/82:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 4/28$470
Sat 9/286:00 amSTL - PTY
1 stop6h 55mDelta
Sat 10/52:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 4/28$490
Wed 7/316:00 amSTL - PTY
1 stop6h 55mDelta
Mon 8/52:25 pmPTY - STL
1 stop9h 14mDelta
Deal found 4/28$565

Cheap American Airlines flights from St. Louis to Panama City

Explore cheap flight options specifically provided by American Airlines for the route between St. Louis and Panama City. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,944,896 searches. Data last updated April 29, 2024.
To aid your search, here are some of the cheapest American Airlines flights we've found from St. Louis to Panama City. Deals are refreshing constantly so come back soon for more options.
Tue 9/242:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Tue 10/81:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 4/28$451
Tue 9/35:30 amSTL - PTY
2 stops8h 44mAmerican Airlines
Mon 9/301:55 pmPTY - STL
2 stops24h 13mAmerican Airlines
Deal found 4/28$453
Thu 9/266:58 pmSTL - PTY
2 stops17h 35mAmerican Airlines
Thu 10/101:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 4/28$471
Wed 9/42:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Sun 9/81:55 pmPTY - STL
2 stops19h 19mAmerican Airlines
Deal found 4/27$473
Fri 8/304:20 pmSTL - PTY
2 stops20h 13mAmerican Airlines
Wed 9/41:55 pmPTY - STL
2 stops19h 19mAmerican Airlines
Deal found 4/27$474
Sat 9/282:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Sat 10/51:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 4/28$491
Sat 9/285:31 amSTL - PTY
1 stop7h 02mAmerican Airlines
Sat 10/51:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 4/28$493
Thu 8/16:13 pmSTL - PTY
2 stops19h 54mAmerican Airlines
Wed 8/281:55 pmPTY - STL
2 stops19h 19mAmerican Airlines
Deal found 4/27$494
Thu 6/65:38 pmSTL - PTY
2 stops18h 51mAmerican Airlines
Tue 6/113:10 pmPTY - STL
2 stops19h 22mAmerican Airlines
Deal found 4/27$513

Cheap St. Louis to Panama City flights in April & May 2024

Find cheap flight options from St. Louis to Panama City specifically for the months of April and May 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,944,896 searches. Prices were last updated on April 29, 2024.
Scroll through some of the best deals on flights from St. Louis to Panama City in 2024. For more flight deals, be sure to check back very soon.
Sun 5/57:30 pmSTL - PTY
2 stops25h 15mMultiple Airlines
Wed 5/155:40 pmPTY - STL
2 stops23h 49mMultiple Airlines
Deal found 4/28$477
Tue 4/306:04 amSTL - PTY
1 stop6h 47mDelta
Wed 5/82:13 pmPTY - STL
1 stop9h 27mDelta
Deal found 4/28$490
Tue 4/305:25 pmSTL - PTY
2 stops19h 35mAmerican Airlines
Wed 5/81:25 pmPTY - STL
2 stops20h 28mAmerican Airlines
Deal found 4/28$493
Sun 5/55:35 pmSTL - PTY
2 stops22h 31mUnited Airlines
Wed 5/1510:00 amPTY - STL
1 stop12h 45mUnited Airlines
Deal found 4/28$494
Sun 5/54:57 pmSTL - PTY
1 stop23h 09mUnited Airlines
Wed 5/1510:00 amPTY - STL
1 stop12h 45mUnited Airlines
Deal found 4/28$499
Thu 5/96:19 amSTL - PTY
1 stop12h 18mUnited Airlines
Sun 5/1210:00 amPTY - STL
1 stop12h 45mUnited Airlines
Deal found 4/27$510
Sun 5/57:30 pmSTL - PTY
2 stops25h 15mMultiple Airlines
Wed 5/1511:40 amPTY - STL
3 stops29h 49mMultiple Airlines
Deal found 4/28$528
Thu 5/96:19 amSTL - PTY
1 stop12h 18mUnited Airlines
Sun 5/123:40 pmPTY - STL
2 stops24h 06mUnited Airlines
Deal found 4/28$530
Thu 5/91:01 pmSTL - PTY
2 stops23h 59mAmerican Airlines
Sun 5/121:50 pmPTY - STL
2 stops19h 12mAmerican Airlines
Deal found 4/27$534

St. Louis to Panama City 2024 flight deals

Discover exclusive flight deals for travel between St. Louis and Panama City in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,944,896 searches. Data last updated April 29, 2024.
Scroll through some of the best deals on flights from St. Louis to Panama City in 2024. For more flight deals, be sure to check back very soon.
Wed 9/256:00 amSTL - PTY
1 stop6h 55mDelta
Tue 10/82:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 4/28$450
Tue 9/242:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Tue 10/81:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 4/28$451
Tue 9/35:30 amSTL - PTY
2 stops8h 44mAmerican Airlines
Mon 9/301:55 pmPTY - STL
2 stops24h 13mAmerican Airlines
Deal found 4/28$453
Wed 9/256:15 amSTL - PTY
1 stop8h 04mUnited Airlines
Mon 10/73:40 pmPTY - STL
2 stops18h 27mUnited Airlines
Deal found 4/28$454
Sun 9/226:00 amSTL - PTY
1 stop6h 55mDelta
Thu 10/102:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 4/28$470
Thu 9/266:58 pmSTL - PTY
2 stops17h 35mAmerican Airlines
Thu 10/101:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 4/28$471
Wed 9/42:38 pmSTL - PTY
2 stops21h 55mAmerican Airlines
Sun 9/81:55 pmPTY - STL
2 stops19h 19mAmerican Airlines
Deal found 4/27$473
Fri 8/304:20 pmSTL - PTY
2 stops20h 13mAmerican Airlines
Wed 9/41:55 pmPTY - STL
2 stops19h 19mAmerican Airlines
Deal found 4/27$474
Sun 5/57:30 pmSTL - PTY
2 stops25h 15mMultiple Airlines
Wed 5/155:40 pmPTY - STL
2 stops23h 49mMultiple Airlines
Deal found 4/28$477

St. Louis to Panama City flights leaving soon

Find last-minute flight options from St. Louis to Panama City for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,944,896 searches. Data last updated April 29, 2024.
Have a look at some of the flights available from St. Louis to Panama City departing last-minute. Tip: verify your flight details before completing your reservation.
Sun 5/57:30 pmSTL - PTY
2 stops25h 15mMultiple Airlines
Wed 5/155:40 pmPTY - STL
2 stops23h 49mMultiple Airlines
Deal found 4/28$477
Sun 5/55:35 pmSTL - PTY
2 stops22h 31mUnited Airlines
Wed 5/1510:00 amPTY - STL
1 stop12h 45mUnited Airlines
Deal found 4/28$494
Sun 5/54:57 pmSTL - PTY
1 stop23h 09mUnited Airlines
Wed 5/1510:00 amPTY - STL
1 stop12h 45mUnited Airlines
Deal found 4/28$499
Sun 5/57:30 pmSTL - PTY
2 stops25h 15mMultiple Airlines
Wed 5/1511:40 amPTY - STL
3 stops29h 49mMultiple Airlines
Deal found 4/28$528
Sun 5/57:30 pmSTL - PTY
3 stops24h 18mMultiple Airlines
Wed 5/1511:40 amPTY - STL
3 stops29h 49mMultiple Airlines
Deal found 4/28$622

Find flights from St. Louis to Panama City within your budget

Customize your flight search to find flights from St. Louis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,944,896 searches. Data last updated April 29, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$450 - $539

Route

Depart

Return

Price

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/25

1 stop6h 55m

Panama City Tocumen Intl

Thu 10/10

1 stop9h 15m

$450

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Tue 9/24

2 stops21h 55m

Panama City Tocumen Intl

Tue 10/8

2 stops20h 09m

$451

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Tue 9/3

2 stops8h 44m

Panama City Tocumen Intl

Mon 9/30

2 stops24h 13m

$453

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/25

1 stop8h 04m

Panama City Tocumen Intl

Mon 10/7

2 stops18h 27m

$454

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sun 9/22

1 stop6h 55m

Panama City Tocumen Intl

Tue 10/8

1 stop9h 15m

$470

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Thu 9/26

2 stops17h 35m

Panama City Tocumen Intl

Thu 10/10

2 stops20h 09m

$471

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 9/28

1 stop6h 55m

Panama City Tocumen Intl

Sat 10/5

1 stop9h 15m

$490

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Thu 5/9

1 stop12h 18m

Panama City Tocumen Intl

Sun 5/12

1 stop12h 45m

$510

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sun 6/9

3 stops25h 50m

Panama City Tocumen Intl

Fri 6/14

2 stops19h 48m

$539

Flights are sorted by cheapest first

Deals found on 4/28

When is the best time to book a flight from St. Louis to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Panama City. Price data was last updated on January 28, 2024.
The best time to book flights from St. Louis to Panama City is 2 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Search Deals

When is the cheapest time to fly from St. Louis to Panama City?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Panama City. Price data was last updated on April 21, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their St. Louis to Panama City flight should consider departing on Monday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Average price of flights to Panama City by month

Plan your trip from St. Louis to Panama City by taking into account the cheapest months to travel. The average price of a one-way flight from St. Louis to Panama City is currently $0 while a round-trip flight costs $476. Price data was last updated on April 21, 2024.

Currently, October is the cheapest month in which you can book a flight from St. Louis to Panama City (average of $474). Flying from St. Louis to Panama City in June is currently the most expensive (average of $590). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

January

$500

February

$525

March

$565

April

$503

May

$496

June

$590

July

$588

August

$507

September

$478

October

$474

November

$484

December

$551

Temperature and rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average temperature and rainfall totals by month.

PTY

Temperature

78.8 - 80.6 °F

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 29, 2024.
Read through reviews of airlines operating flights from St. Louis to Panama City, such as Delta, American Airlines and United Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.1
Very good
10,932 reviews
Check prices

Comfort

7.9

Overall

8.1

Food

7.4

Entertainment

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Terrible flight crew that skipped our row for service multiple times.

Delta
8.1
Very good
10,932 reviews
Delta
8.1
Very good
10,932 reviews
Check prices

Comfort

7.9

Overall

8.1

Food

7.4

Entertainment

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Terrible flight crew that skipped our row for service multiple times.

United Airlines
7.4
Good
11,221 reviews
Delta
8.1
Very good
10,932 reviews
Check prices

Comfort

7.9

Overall

8.1

Food

7.4

Entertainment

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Terrible flight crew that skipped our row for service multiple times.

American Airlines
7.3
Good
14,844 reviews
Delta
8.1
Very good
10,932 reviews
Check prices

Comfort

7.9

Overall

8.1

Food

7.4

Entertainment

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Terrible flight crew that skipped our row for service multiple times.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find flights from St. Louis to Panama City for under $500 on Cheapflights?

    Yes, there are multiple flights from St. Louis to Panama City for under $500. The cheapest flight booked recently is on Delta for just $450, but on average you can expect to pay $496.

  • Are there last-minute flights available from St. Louis to Panama City for under $500?

    There are currently 5+ open flights from St. Louis to Panama City within the next 7 days for less than $500.

  • What are the cheapest airlines flying from St. Louis to Panama City round-trip?

    Cheapflights users have booked flights from St. Louis to Panama City round-trip from $450. Other airlines that can offer you cheap pricing are American Airlines, from $451, and United Airlines, from $454. Delta is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most popular airlines that fly from St. Louis to Panama City?

    Before booking your flight from St. Louis to Panama City check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

  • What does STL to PTY mean?

    STL stands for Lambert-St Louis Airport, while PTY stands for Panama City Tocumen Intl Airport. These codes are often called IATA codes, a set of identifiers established by IATA (International Air Transport Association) that is widely used by airlines and the aviation industry.

  • Can I find deals for flights from St. Louis to Panama City that include extra baggage allowance?

    The amount of baggage you can bring on your St. Louis to Panama City flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from St. Louis to Panama City with specific airlines?

    Yes, Cheapflights allows you to browse and filter St. Louis to Panama City flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from St. Louis to Panama City that include hotel bookings?

    Yes. In addition to deals on St. Louis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama City.

  • Can I find deals for business class flights from St. Louis to Panama City?

    Yes. Cheapflights offers flight deals from St. Louis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from St. Louis to Panama City that allow pets onboard?

    Many airlines flying from St. Louis to Panama City offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from St. Louis to Panama City?

    Yes, you can often find last-minute deals on St. Louis to Panama City flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the St. Louis to Panama City flight deals updated?

    The St. Louis to Panama City flight deals you see on this page were last updated on 4/28.

See more FAQs

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Alternative routes for St. Louis to Panama City
See prices for flight routes from nearby airports that may be better suited for you.

Kansas City to Panama City flights
Springfield to Panama City flights

Top 3 airlines flying from St. Louis to Panama City

Discover the top 3 airlines that operate flights from St. Louis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,944,896 searches. Data last updated April 29, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$499FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
United AirlinesCheapest$349Average$402FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
American AirlinesCheapest$362Average$544FlexibilityNo cancel feeOn-time71%
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Search flights from St. Louis to Panama City by cabin class

Find flights from St. Louis to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from St. Louis to Panama City?

Deals for St. Louis to Panama City flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from St. Louis to Panama City?

Cheapflights simply makes it quick and affordable to book flights from St. Louis to Panama City by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from St. Louis to Panama City with no change fees?

Yes, we can. To see specific flights from St. Louis to Panama City with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from St. Louis to Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from St. Louis today and book when prices fit your budget.

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